Université de BordeauxCluster of excellence

Challenges and strategy


Four main obstacles hindered our ability to identify relevant underlying neurobiological alterations:

  • The absence of animal models able to reproduce the complexity of the symptoms of these psychopathologies
  • The lack of adapted technological tools to appropriately investigate the underlying neurobiological mechanisms of these behavioral pathologies
  • The unavailability of sufficient material resources
  • The lack of federation of human expertise, which is necessary to a transnosographic study of pathologies that share common dimensions

OptoPath Strategy

  • Creating and coupling Cutting edge tools for in vivo brain activity recording and manipulationin behaving rodents
  • Developing new high face validity behavioural models of Addiction, Obesity, PTSD and Memory Deficits

 Combined mode commutator

 Optogenetic on self-administration set-up

 Multi-modal eating behavior box